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May 1948

The Postnatal Development of the Human Cerebral Cortex.

Arch NeurPsych. 1948;59(5):687-688. doi:10.1001/archneurpsyc.1948.02300400123016

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Abstract

The present volume represents the continuation of a long term study of the cytoarchitecture of the human cerebral cortex, the first and second parts of which were published in 1939 and 1941. Similar technical methods were used throughout, permitting comparison of the development of the cortex in the newly born, the 1 month and the 3 month old infant. Development is judged according to histologic criteria, which include number and size of cells, amount of chromaphil substance, degree of myelination and the structure of cellular processes.

The underlying concept is that a correlation may be made between maturation of function and observed structural changes and that this correlation may be made with respect not only to specific areas of the brain but even to layers and individual cells. Point to point correspondence and discrete localization of function in the brain are implicit in this approach. Thus, according to structural criteria,

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