IN THE EPIDEMIC of acute poliomyelitis in Nebraska in 1946, we performed autopsies in 14 cases of the bulbar type of this disease. The gross lesions in the central nervous system were unexpected in that there was an unusual amount of hemorrhagic change. This prompted a study of the nature of these hemorrhagic lesions.
METHODS AND MATERIAL
Autopsies were performed two to ten hours post mortem in hot weather. The pathologic observations (except for those in the central nervous system) are given in table 1.
Central Nervous System.—
Fourteen brains and 13 spinal cords were ex- amined. The brains and cords, after initial examination, were suspended in solution of formaldehyde U.S.P. (1:4) for three weeks or longer. The brains were then sectioned coronally and the cords transversely. Sections for histologic study were taken from the frontal, parietal and occipital lobes; basal ganglia; thalamus; midbrain; cerebellum; pons; medulla, and cervical, thoracic
LEV M, RUDEN SJ, REALS WJ. HEMORRHAGIC LESIONS IN THE CENTRAL NERVOUS SYSTEM IN ACUTE POLIOMYELITIS. Arch NeurPsych. 1948;60(2):182-195. doi:10.1001/archneurpsyc.1948.02310020078006