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January 1950

ELECTROENCEPHALOGRAPHIC STUDIES ON EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN RHESUS MONKEYS

Author Affiliations

NEW YORK

From the Department of Neuropathology and the Division of Electroencephalography of the New York State Psychiatric Institute and Hospital.

Arch NeurPsych. 1950;63(1):125-132. doi:10.1001/archneurpsyc.1950.02310190131011
Abstract

THERE are relatively few electroencephalographic studies on inflammatory and demyelinating diseases of the nervous system.

Berger1 observed normal tracings in cases of epidemic encephalitis; his findings were corroborated by Schwab and Cobb.2 Gibbs and Gibbs,3 however, studying cases of severe acute encephalomyelitis, reported continuous slow waves which may be generalized over the entire cortex or located predominantly over a particular zone, thereby suggesting a focus. Lindsley and Cutts4 observed a case of encephalitis in a 10 year old boy with repeated electroencephalograms. During the acute phase the record showed continuous slow activity; this abnormality gradually decreased to normal when the symptoms disappeared. Ross5 noted large slow waves, often bilaterally synchronous, in 4 children with acute encephalitis and meningoencephalitis. These slow waves persisted beyond the acute phase of the disease and were not closely related to the severity of the clinical picture. In 240 cases of

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