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October 1950

SERUM NEURITISReport of Two Cases and Brief Review of the Syndrome

Author Affiliations

Fellow in Medicine, Mayo Foundation; ROCHESTER, MINN.

AMA Arch NeurPsych. 1950;64(4):568-573. doi:10.1001/archneurpsyc.1950.02310280080008

MOST physicians are well aware that anaphylaxis and serum sickness may result from the prophylactic use of serum, but it is not well recognized that a disabling neuritis1 may also follow. This neuritis comprises a definite syndrome and, if treated properly, has a good prognosis. Since the prophylactic use of various serums is still common, it seems worth while to report 2 cases of tetanus antitoxin neuritis recently encountered within a period of one month at the Mayo Clinic.


Case 1.  —A white man aged 36 entered the clinic on Jan. 4, 1950, with the chief complaint of inability to lift the right shoulder and arm.The patient had been apparently well until Oct. 29, 1949, when he incurred a minor pitchfork wound in the right foot. The same day, his family physician administered an injection of tetanus antitoxin just below the deltoid area in the