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May 1952

COMBINED USE OF ETHYL ALCOHOL AND AMOBARBITAL (AMYTAL®) SODIUM FOR AMBULATORY NARCOANALYSIS

Author Affiliations

WASHINGTON, D. C.

From Howard University College of Medicine, Division of Neuropsychiatry.

AMA Arch NeurPsych. 1952;67(5):620-624. doi:10.1001/archneurpsyc.1952.02320170038005
Abstract

ONE OF the principal problems encountered in employing drugs such as amobarbital (amytal®) sodium or thiopental (pentothal®) sodium for ambulatory narcoanalysis is that patients may sometimes become immobilized for several hours or longer, owing to the hypnotic action of the drug. This, obviously, makes it hazardous to release such patients from the clinic prior to recovery from the effects of the drug. Another problem is that of administering the optimum dose so as to obtain a satisfactory twilight narcosis and not to induce sleep. Much valuable clinic time is often spent in attempting to revive patients in whom deep sleep has been induced. In order to avoid overdosage and to maintain the proper level of therapeutic narcosis it has been necessary to inject these drugs very slowly and to repeat the injection. In addition, tolerance to barbiturates may vary considerably. Even with the barbiturates above mentioned, the differences

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