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May 1952

CLINICAL AND ELECTROENCEPHALOGRAPHIC EFFECTS OF PREFRONTAL LOBOTOMY AND TOPECTOMY IN CHRONIC PSYCHOSES

Author Affiliations

NEW YORK

From the Neurosurgical Section, Veterans Hospital, Bronx, N. Y. (Dr. Krueger).; From the Neuropsychiatric Service, Veterans Administration Hospital, Bronx, N. Y. (Dr. Wayne).

AMA Arch NeurPsych. 1952;67(5):661-671. doi:10.1001/archneurpsyc.1952.02320170079011
Abstract

THIS REPORT deals with clinical and electroencephalographic observations on, and is a part of a comparative study of, the effects of prefrontal lobotomy and topectomy in a group of 105 patients with chronic psychoses who were admitted to the Veterans Administration Hospital, Bronx, New York, for psychosurgical procedures over a period from March, 1947, to December, 1950.

CLINICAL OBSERVATIONS 

Case Material and Procedures.  —With the exception of one patient with manic-depressive psychosis, all had chronic advanced schizophrenia of paranoid, hebephrenic, or catatonic type. A comparative study of the effects of prefrontal lobotomy and topectomy seemed to be particularly applicable in a rather homogeneous group of patients with advanced schizophrenia. A selection of the patients for one or the other procedure was deliberately avoided. All 105 patients—84 from the Northport Veterans Administration Hospital, 17 from the Canandaigua Veterans Administration Hospital, and four from other hospitals—were selected for psychosurgical procedures by the

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