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June 1952

INTRACRANIAL ANEURYSMSClinicopathologic Considerations of Oculomotor-Nerve Regeneration and Intracerebral Hemorrhage

Author Affiliations


From the Department of Neuropsychiatry, Southwestern Medical School of the University of Texas; Baylor University Hospital, and Veterans Administration Hospital.

AMA Arch NeurPsych. 1952;67(6):771-786. doi:10.1001/archneurpsyc.1952.02320180048007

THE LITERATURE concerned with saccular aneurysms of the cerebral arteries deals predominantly with the syndromes these lesions present, diagnostic procedures, of which arteriography receives a warranted emphasis, and a growing contingent of reports on prognosis and the results of surgical intervention. Pathologic studies concern chiefly the histologic processes responsible for aneurysmal formation, with a smaller number of reports on changes in the meninges and the topographic distribution of the hemorrhagic foci resulting from intracerebral hemorrhage. There is a dearth of information on the late changes in the nervous system following the various manifestations of cerebral aneurysm. It has been my good fortune to observe two patients with such residual lesions. In the first patient the oculomotor regenerative syndrome of the "pseudo-Graefe phenomenon," of comparatively insidious origin, was present, and the rootlets of the third cranial nerve showed definite evidence of axonal neoformation; in the other, a subcortical hemorrhagic cyst was