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February 1953

PROGRESSIVE BULBAR PARALYSIS SHOWING HEREDOFAMILIAL INCIDENCE AND INTELLECTUAL IMPAIRMENT

Author Affiliations

Lond. EDINBURGH, SCOTLAND

AMA Arch NeurPsych. 1953;69(2):197-207. doi:10.1001/archneurpsyc.1953.02320260055004
Abstract

HEREDOFAMILIAL incidence has only rarely been reported in cases of progressive bulbar paralysis occurring in adult life. Equally rare is the reported coincidence of marked intellectual deterioration with this disease process. Both these unusual manifestations were found in the following case, which seems, therefore, worthy of detailed description and discussion.

REPORT OF A CASE  Mrs. C. S., aged 69, was admitted to the Royal Edinburgh Hospital for Mental and Nervous Disorders, West House, on March 26, 1950. She died on April 26, 1950.

Family History.—  The maternal ancestry was distinguished for good health and longevity, the mother of the patient dying at the age of 91. The paternal line was described in the locality from which they hailed as possessing "a nervous streak" (Chart). The father of the patient died at the age of 69. The stated cause of death was "progressive muscular atrophy." The commencing symptoms were difficulty in

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