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January 1956

The Neurological Complications of Behcet's Syndrome

Author Affiliations

Cardiff, South Wales

From the Bridgend General Hospital, and the Department of Neurology, Welsh National School of Medicine.

AMA Arch NeurPsych. 1956;75(1):1-14. doi:10.1001/archneurpsyc.1956.02330190009001

Since 1930 a syndrome has gradually been recognized which is characterized by recurrent iritis (often with hypopyon) and ulceration of the mouth and genitalia. Most of the early reports are to be found in the French and German literature, but in the last few years the condition has attracted attention in this country and in America. Although usually first seen by the ophthalmologist, dermatologist or gynecologist, these patients may develop serious symptoms of considerable interest to the neurologist. We intend to review the main clinical features of this disorder and shall lay particular emphasis on the neurological disturbances that may occur, and even prove fatal. Two personally observed cases, with unusual cerebral and spinal complications, will be described. An attempt will then be made to define the pattern of involvement of the nervous system in this condition. The pathological evidence will be reviewed and comments made on the question of