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September 1957

Depressive and Paranoid ReactionsApplication of Adaptational Principles to Their Understanding

Author Affiliations

New York

From the Section of Research Psychiatry, Sloan-Kettering Institute, and the Neuropsychiatric Service, Memorial Hospital, Memorial Center for Cancer and Allied Diseases.

AMA Arch NeurPsych. 1957;78(3):301-311. doi:10.1001/archneurpsyc.1957.02330390083011

The Section of Research Psychiatry at Sloan-Kettering Institute and the Neuropsychiatric Service at Memorial Hospital have conducted studies of patients who have undergone abdominoperineal resection,9 radical mastectomy,2 total gastrectomy, or hysterectomy,5 to identify the psychological problems associated with cancer and specific surgical procedures. The major purposes of these investigations were to determine the measures which could be employed (1) to reduce the incidence and severity of postoperative hypochondriasis with associated curtailment of activity, and (2) to provide a rationale for the establishment of a rehabilitation program for patients with cancer.

During the course of research with the above objectives the development of major psychiatric disorders other than hypochondriacal reactions has been observed. Depressive and paranoid reactions have been observed where there was no evidence of their prior occurrence in such form. This development does not imply, however, that the potential for psychopathology was not present, or even