Arteriovenous aneurysms in the arteries of the extremities may cause large arteriovenous shunts, increasing the minute volume of the heart and thereby its work. If such a shunt is permitted to continue long, it may cause cardiac insufficiency (high) output failure). Experimental arteriovenous aneurysm has been used to induce cardiac insufficiency. Many separate observations on patients with intracranial arteriovenous aneurysms and cardiac symptoms, especially cardiac insufficiency, have been published in which the opinion was expressed that the aneurysm had caused the cardiac symptoms. It is open to discussion, however, whether or not the heart complications one sees in patients with intracranial aneurysms are actually due to overloading of the heart resulting from a large arteriovenous shunt (Schlesinger and Hazen44).
In order to study this question in greater detail, 14 cases of arteriovenous aneurysm were subjected to thorough cardiovascular investigation. In addition, the histories of 123 patients with arteriovenous aneurysm
HÖÖK O, WERKÖ L, ÖHRBERG G. Intracranial Arteriovenous AneurysmsA Study of Their Effect on the Cardiovascular System. AMA Arch NeurPsych. 1958;79(6):622-632. doi:10.1001/archneurpsyc.1958.02340060018002