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February 24, 1999

Use of Antiretroviral Therapy by Intravenous Drug Users With HIV—Reply

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;281(8):699-701. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-8-jbk0224

In Reply: Dr Mannheimer and colleagues provide data that demonstrate the major recommendation from our study on ART use among out-of-treatment IDUs, which is that appropriate use of combination therapy can be effectively promoted in conjunction with other treatment services. Methadone maintenance treatment provides an opportunity to provide HIV care1 and may reduce concerns with nonadherence to ART regimens by approximating directly observed therapy.2 If the shortage of drug treatment slots can be ameliorated, as has recently been called for by Gen Barry McAfferty, Office of National Drug Control Policy, HIV-infected IDUs may more easily access ART.3

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