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February 24, 1999

HELLP Syndrome

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;281(8):703-705. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-8-jbk0224

To the Editor: Dr Stone1 presented a typical case of the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) that occurred in his wife. After she gave birth her condition continued to deteriorate to the point that she required aggressive medical therapy. Our data on the relationship between thrombocytopenia and the HELLP syndrome2 suggest that monitoring the platelet count before delivery may help to identify women at an increased risk of this syndrome and, thus, help to avoid the risk of serious complications and the need for aggressive therapy postnatally.

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