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March 10, 1999

Effects of Methylmercury Exposure on Neurodevelopment

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor


Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999

JAMA. 1999;281(10):896-897. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-10-jac90000

To the Editor: Dr Davidson and colleagues1 reported no significant association between neurological developmental deficits and gestational exposure to MeHg in their Seychelles study. They largely dismiss the relevance to US consumers of positive associations observed in a similar study in the Faroe Islands2 and suggest that fish consumption advisories for ocean fish in US markets are not warranted. They postulate different exposure patterns as a likely explanation for contradictory findings, with Faroese episodically consuming pilot whale with high concentrations of MeHg (1.6 ppm) and Seychellois regularly consuming fish with lower concentrations. We call attention to several issues regarding exposure patterns and metrics.

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