Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor
Copyright 1999 American Medical Association.
All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999
In Reply: Drs Grandjean and White
and Drs Stern and Gochfeld question the significance of our study of
MeHg exposure from fish consumption in the Seychelles Islands. We
believe the issues they raise are opinions not based on scientific
First, hair is well established and widely used as a biological marker
for MeHg exposure and was recommended as the measure of choice by the
World Health Organization. Hair correlates with brain levels and has a
smaller coefficient of variation (percent error) than
blood.1 Longitudinal analysis of hair allows the
recapitulation of exposure during the entire period of pregnancy.
Davidson PW, Myers GJ, Cox C, Cernichiari E, Clarkson TW, Shamlaye C. Effects of Methylmercury Exposure on Neurodevelopment—Reply. JAMA. 1999;281(10):896-897. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-10-jac90000