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April 14, 1999

Postexposure Prophylaxis Following HIV Exposure

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;281(14):1269. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-14-jac90002

To the Editor: The article by Dr Lurie and colleagues1 on postexposure prophylaxis (PEP) for persons exposed to human immunodeficiency virus (HIV) in nonoccupational settings raises important clinical and public health issues. However, the methods suggested to determine the likelihood that the source patient is HIV positive, including use of local research studies and seroprevalence data, are problematic.

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