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May 5, 1999

Intensive vs Clinical Follow-up After Treatment of Primary Breast Cancer: 10-Year Update of a Randomized Trial

JAMA. 1999;281(17):1586. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-17-jbk0505

To the Editor: Two randomized trials performed in Italy1,2 failed to show any impact of intensive diagnostic follow-up on 5-year mortality for patients with primary breast cancer. We have now evaluated the mortality at 10 years in 1 of these large trials, designed to compare the effectiveness of 2 alternative follow-up protocols (intensive vs clinical) offered to study participants during the first 5 years after the treatment of primary breast cancer.

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