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June 9, 1999

Cost-effectiveness of Interferon Treatment for Hepatitis C

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;281(22):2083-2084. doi:10.1001/jama.281.22.2083

To the Editor: Dr Wong and colleagues1 examined the cost-effectiveness of management strategies for patients with chronic hepatitis C, and the authors concluded that a 12-week initial empirical trial of interferon alfa-2b is a "reasonable management strategy." Given a purported prevalence of some 4 million people in the United States infected with hepatitis C, of whom a significant number may have chronic hepatitis and be candidates for therapy, this is not a trivial recommendation.

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