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July 14, 1999

Effect of Lifestyle Changes on Coronary Heart Disease—Reply

JAMA. 1999;282(2):130-132. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-2-jbk0714

In Reply: Dr Herbert is correct: usual care for control group patients changed during the Lifestyle Heart Trial, but not as much as in the experimental group. Sixty percent of control group patients took lipid-lowering drugs between years 1 and 5, lowering their LDL cholesterol (Table 2 of our article presents baseline, 1-year, and 5-year adherence in each group). These moderate changes in lifestyle and medication did not go far enough to stop progression of CAD in most patients.1

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