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July 21, 1999

Garcinia cambogia for Weight Loss

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;282(3):233-235. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-3-jac90006

To the Editor: Dr Heymsfield and colleagues1 reported that "Garcinia cambogia failed to produce significant weight loss and fat mass loss [in humans] beyond that observed with a placebo," while previous reports indicate that G cambogia HCA decreases appetite, reduces food intake, and inhibits fat synthesis in animals,2,3 and reduces body weight, triglycerides, and cholesterol levels in humans.4 Why the disparity?

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