Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor
To the Editor: Dr Heymsfield and colleagues1 reported that "Garcinia cambogia failed to produce significant weight loss and fat mass loss [in humans]
beyond that observed with a placebo," while previous reports indicate that G cambogia HCA decreases appetite, reduces food intake,
and inhibits fat synthesis in animals,2,3
and reduces body weight, triglycerides, and cholesterol levels in humans.4 Why the disparity?
Schaller JL. Garcinia cambogia for Weight Loss. JAMA. 1999;282(3):233-235. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-3-jac90006