Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor
To the Editor: Ovarian hyperstimulation syndrome
is one of the most severe complications following controlled ovarian stimulation.
Fluid redistributes from intravascular to extravascular spaces (ie, the abdominal
or pleural cavity) leading to ascites and pleural effusions. Most patients
can be treated successfully with intravascular fluids and thrombosis prophylaxis.
However, complications such as thrombosis and even death have been reported.1 We report the first case, to our knowledge, of
a patient with myocardial infarction after ovarian hyperstimulation syndrome.
Ludwig M, Tölg R, Richardt G, Katus HA, Diedrich K. Myocardial Infarction Associated With Ovarian Hyperstimulation Syndrome. JAMA. 1999;282(7):632-633. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-7-jbk0818