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August 25, 1999

Aspirin and Risk of Hemorrhagic Stroke

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;282(8):731-733. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-8-jbk0825

To the Editor: Dr He and colleagues1 reported a meta-analysis of collaborative trials on the risks and benefits of aspirin therapy. While they found an increased risk of hemorrhagic stroke, this risk may be outweighed by the benefits of aspirin therapy. Dr Boissel,2 in an accompanying editorial, wisely emphasizes patient selection as a sensible approach, particularly in identifying candidates for primary prevention of vascular events with aspirin therapy.

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