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September 22/29, 1999

Diabetes and Decline in Heart Disease Mortality

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;282(12):1132. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-12-jbk0922

To the Editor: Dr Gu and colleagues1 found that patients with diabetes experienced fewer declines in heart disease mortality in 1982-1984 vs 1971-1975, compared with nondiabetic individuals during the same periods, and suggest that the incidence of coronary heart disease may have decreased less in patients with diabetes. However, since weight gain is a known complication of insulin and oral hypoglycemic agents, it is possible that weight gain and associated hyperlipidemia secondary to medical management is preventing individuals with type 2 diabetes from fully participating in the declining mortality from coronary heart disease.

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