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October 13, 1999

Childbirth History

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;282(14):1334. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-14-jbk1013

To the Editor: Highly active antiretroviral therapy (HAART) has been shown to decrease mortality and morbidity in persons infected with human immunodeficiency virus, but adherence to the regimen is essential to a successful outcome.1,2 With the widespread use of protease inhibitors, directly observed therapy (DOT) with these medications has been proposed.35 This strategy has proven successful in enhancing medication adherence among marginalized populations with tuberculosis.6

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