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November 3, 1999

Environmental Cancer

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;282(17):1625. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-17-jbk1103

To the Editor: Stored tissue has traditionally been a rich, readily available source of material for research. Although requirements for informed consent were spelled out in the Common Rule,1 the issue of consent for tissue banking gained prominence when the Centers for Disease Control and Prevention considered performing genetic research on its extensive collection of samples. A panel, convened to discuss how best to handle consent for research, published a Consensus Statement in a 1995 article in JAMA.2 Pathologists and epidemiologists expressed concern that the new emphasis on consent would negatively affect accrual.3,4 This concern generated a flurry of responses and position papers.5,6

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