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November 10, 1999

Hypovolemia in Patients With Hyperglycemia

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthorStephenLurieMD, PhDIndividualAuthor

JAMA. 1999;282(18):1720-1721. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-18-jbk1110

To the Editor: In their article on the physical diagnosis of hypovolemia, Dr McGee and colleagues1 correctly state that dehydration refers to "the losses of intracellular water that ultimately cause cellular desiccation and elevate the plasma sodium concentration and osmolality." The authors note that while patients with pure dehydration may lack circulatory instability, most patients presenting with dehydration also have hypovolemia. Furthermore, they indicate that patients with pure dehydration should receive 5% dextrose, usually more slowly than patients with hypovolemia, who require a rapid infusion of 0.9% saline.

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