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November 17, 1999

Regular Exercise and Subclinical Myocardial Injury During Prolonged Aerobic Exercise

Author Affiliations

Phil B.FontanarosaMD, Interim CoeditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephenLurieMD PhD, Fishbein FellowIndividualAuthor

JAMA. 1999;282(19):1816. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-19-jbk1117

To the Editor: Physicians increasingly are encouraged to prescribe moderate or vigorous intensity physical activity for their patients.1 However, prolonged aerobic exercise may cause myocardial damage manifested immediately after exercise as a rise in cardiac troponin T (cTnT) and cardiac troponin I levels and wall motion abnormalities detected by echocardiography.2 We conducted a study to determine whether modest physical activity is sufficient to protect against subclinical myocardial injury caused by excessive exercise.

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