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November 24, 1999

The Crisis in Clinical Research

Author Affiliations

Phil B.FontanarosaMD, Interim CoeditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephenLurieMD PhD, Fishbein FellowIndividualAuthor


Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999

JAMA. 1999;282(20):1913-1916. doi:10.1001/jama.282.20.1913

To the Editor: I take exception to the definition of clinical research offered by Dr Nathan1 as "patient-oriented research." This misnomer fails to acknowledge the significant conflict inherent in clinical research between a physician-scientist's devotion to the promotion of health for the individual patient and allegiance to the outcome of human research.

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