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November 24, 1999

The Crisis in Clinical Research—Reply

Author Affiliations

Phil B.FontanarosaMD, Interim CoeditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephenLurieMD PhD, Fishbein FellowIndividualAuthor

JAMA. 1999;282(20):1913-1916. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-20-jbk1124

In Reply: I am clearly in agreement with Dr Nathan and the NIH panel1 that academic clinical research in the United States is in decline and that changes in our "national commitment" are needed to try to rectify this situation. I differ in my perception of the severity of the situation, especially with regard to NIH-funded programs, and the urgency for large, bold new initiatives that might reverse the continuing loss of patient-oriented research.

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