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December 15, 1999

Preventing Prion Transmission in Corneal Transplants—Reply

Author Affiliations

Phil B.FontanarosaMD, Interim CoeditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephenLurieMD PhD, Fishbein FellowIndividualAuthor

JAMA. 1999;282(23):2211. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-23-jbk1215

In Reply: The transmission of classic CJD via corneal transplantation has been demonstrated, and the potential possibility of transmission of nv-CJD via corneal transplantation should be taken into consideration. With ongoing national efforts to increase organ and tissue donation, we are pleased to hear from Drs Cavanagh and Hogan that the additional safeguards introduced in the new eye donor screening standards and recently approved by the Eye Bank Association of America will ensure the highest standards of safety in this tissue.

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