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March 1, 2000

Rapid Heroin Detoxification Under General Anesthesia

Author Affiliations

Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Fishbein FellowIndividualAuthor

JAMA. 2000;283(9):1143. doi:10.1001/jama.283.9.1137

To the Editor: Great Britain is in the early stages of a new heroin epidemic, often involving very young users.1 Traditionally, treatment for heroin addiction substitutes methadone hydrochloride for heroin, often followed by gradual tapering of the methadone dose. However, this method is often unsuccessful because of high dropout and subsequent relapse rates. Furthermore, most study designs have had limited assessment of clinical outcomes.2

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