Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Fishbein FellowIndividualAuthor
To the Editor: Dr Jüni and colleagues1 illustrated the problem of rating the quality of
clinical trials with summary scores for study quality. We have 3 comments.
First, in 1 of the 25 scales tested, the original authors refused to define
a cut point for quality.2 This was ignored
by Jüni et al, who depicted a point the original authors merely used
for illustration of a graph as a cut point. Within the context of acupuncture
in chronic pain, this graph showed the increasing proportion of negative study
results as the quality score increased. The graph encouraged a flexible definition
of cut points.
ter Riet G, Leffers P, Zeegers M. Scoring the Quality of Clinical Trials. JAMA. 2000;283(11):1421-1423. doi:10.1001/jama.283.11.1421