Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Fishbein FellowIndividualAuthor
To the Editor: Mr Friedberg and colleagues1 found that studies sponsored by drug companies
were less likely to report unfavorable results than studies funded by nonprofit
organizations. The authors posited several alternative explanations for their
findings, including publication bias, unconscious bias because of relationships
between the investigator and the pharmaceutical company, early screening of
studies by drug firms, and direct company involvement with the study design.
Gagnon JP. Sources of Bias in the Economic Analysis of New Drugs. JAMA. 2000;283(11):1423-1424. doi:10.1001/jama.283.11.1421