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March 15, 2000

Vitamin D Deficiency in Women With Hip Fracture—Reply

Author Affiliations

Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Fishbein FellowIndividualAuthor


Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

JAMA. 2000;283(11):1425-1426. doi:10.1001/jama.283.11.1421

In Reply: Vitamin D deficiency has been documented in older patients in nursing homes and residential communities in the United States, but there are few data available on vitamin D levels in women with acute osteoporotic fractures. In our study we found significant differences in vitamin D levels in the women with hip fractures and no known secondary comorbid medical conditions. In contrast, women admitted for elective joint replacement did not show vitamin D deficiency. We rigorously excluded patients with a multitude of risk factors that might predispose to osteoporosis, as indicated in Table 1 of our article. As shown in Figure 1 of our article, we excluded 190 women with comorbid medical conditions or those taking medications that could affect bone. In contrast to the vitamin D deficiency among women with hip fractures, we found that 17% of ambulatory women with osteoporosis by bone density criteria in an osteoporosis program had vitamin D deficiency.1 While many women fall without adverse skeletal effects, fractures are more likely to occur in those who have a low bone density.

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