Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Fishbein FellowIndividualAuthor
Copyright 2000 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2000
To the Editor: Several articles on the clinical
utility of cranberry juice in patients with recurrent urinary tract infections
have been published.1- 3
Older studies attributed antibacterial activity to organic acids such as hippuric
acid.4 However, more recent studies have
emphasized the role of components that act by interference with bacterial
adherence of Escherichia coli.5
Thus, it seemed important to reassess whether cranberry juice has true broad-spectrum
direct antibacterial activity.
Lee Y, Owens J, Thrupp L, Cesario TC. Does Cranberry Juice Have Antibacterial Activity?. JAMA. 2000;283(13):1691. doi:10.1001/jama.283.13.1685