Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Contributing EditorIndividualAuthor
To the Editor: Dr Visser and colleagues1 reported elevated levels of C-reactive protein
(CRP) in otherwise healthy overweight and obese individuals, suggesting a
state of chronic low-grade systemic inflammation. The authors, in their rationale
for measuring CRP, cited studies showing an association between adipose tissue
and the proinflammatory cytokine interleukin 6 (IL-6), but they did not measure
serum concentrations of IL-6.
Vgontzas AN, Bixler EO, Papanicolaou DA, Chrousos GP. Chronic Systemic Inflammation in Overweight and Obese Adults. JAMA. 2000;283(17):2235-2236. doi:10.1001/jama.283.17.2235