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May 3, 2000

Chronic Systemic Inflammation in Overweight and Obese Adults

Author Affiliations

Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Contributing EditorIndividualAuthor


Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

JAMA. 2000;283(17):2235-2236. doi:10.1001/jama.283.17.2235

To the Editor: Dr Visser and colleagues1 reported elevated levels of C-reactive protein (CRP) in otherwise healthy overweight and obese individuals, suggesting a state of chronic low-grade systemic inflammation. The authors, in their rationale for measuring CRP, cited studies showing an association between adipose tissue and the proinflammatory cytokine interleukin 6 (IL-6), but they did not measure serum concentrations of IL-6.

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