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July 5, 2000

Adjunctive Therapies for Wound Healing—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthor

JAMA. 2000;284(1):40-41. doi:10.1001/jama.284.1.39

In Reply: We agree with Drs Bozzuto and Fife that in vitro and animal model data support the positive effects of oxygenation on wound healing. Interestingly, some data also suggest that hypoxia may play a role in wound healing.1 While there are a large number of anecdotal reports pertaining to hyperbaric oxygen and wound healing, there is a dearth of prospective, randomized, double-blind, placebo-controlled studies.

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