Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthor
Copyright 2000 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2000
To the Editor: The article by Dr Bifani and
colleagues1 portrays the role of molecular
epidemiology in the control of tuberculosis. The authors identified a strain
(W4 variant) using multiple genetic markers that provide a definitive phylogenetic
relationship among 43 isolates from patients in New Jersey. They also identified
a more distant relationship between these isolates and the W strain, the cause
of numerous outbreaks of drug-resistant tuberculosis in New York.
Fontanarosa PB, Braden CR, Onorato IM, Crawford JT. Molecular Epidemiology and Tuberculosis Control. JAMA. 2000;284(3):305-307. doi:10.1001/jama.284.3.303