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July 19, 2000

Molecular Epidemiology and Tuberculosis Control

Author Affiliations

Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthor

JAMA. 2000;284(3):305-307. doi:10.1001/jama.284.3.303

To the Editor: The article by Dr Bifani and colleagues1 portrays the role of molecular epidemiology in the control of tuberculosis. The authors identified a strain (W4 variant) using multiple genetic markers that provide a definitive phylogenetic relationship among 43 isolates from patients in New Jersey. They also identified a more distant relationship between these isolates and the W strain, the cause of numerous outbreaks of drug-resistant tuberculosis in New York.

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