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Letters
August 23/30, 2000

Breastfeeding in Women With HIV

Author Affiliations
 

Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(8):956-957. doi:10.1001/jama.284.8.956

To the Editor: Dr Nduati and colleagues1 present evidence to support the importance of very early postnatal human immunodeficiency virus type 1 (HIV-1) transmission through breastfeeding. However, differences between the trial arms in HIV-1 infection rates at birth and soon after raise a potential source of bias. Randomization to breastfeed or formula feed at 32 weeks of pregnancy may have led to differences in behavioral or biological risk factors for intrapartum or late prenatal HIV-1 transmission.2,3 Women with HIV-1 who agreed to be randomized and were assigned to the formula feeding arm (213/2315 = 9% of the entire sample of HIV-1–seropositive women) received free formula and instruction sessions in late pregnancy on boiling water and minimizing bacterial contamination.

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