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September 20, 2000

Aspirin in Acute Ischemic Stroke—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(11):1379. doi:10.1001/jama.284.11.1378

In Reply: The purpose of our Editorial was to discuss the results of the ancrod trial and not the relative efficacy of aspirin in acute stroke. Aspirin has not been approved by the US Food and Drug Administration to treat acute stroke.

The relative benefits and safety of aspirin either combined with or in comparison to ancrod, tPA, or any other new stroke therapy can only be determined from a randomized controlled trial.

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