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October 18, 2000

Problems in Pharmacoeconomic Analyses—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(15):1922-1924. doi:10.1001/jama.284.15.1921

To the Editor: The experience of the Comitato Inter-Ministeriale Programmazione Economica (CIPE) of the Italian Ministry of Health (the body responsible for national drug reimbursement negotiations) is similar to that of Dr Hill and colleagues.1 From January 1999 to April 2000, we reviewed 212 applications by the pharmaceutical industry, of which fewer than 10% included a pharmacoeconomic analysis. We identified 2 consistent aspects of inadequate pharmacoeconomic methodology.

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