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December 13, 2000

Biochemical Outcomes of Treatment for Prostate Cancer

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(22):2869. doi:10.1001/jama.284.22.2869

To the Editor: Dr D'Amico and colleagues1 reported that patients at intermediate and high risk of prostate-specific antigen (PSA) failure had better PSA outcomes if they were treated with radiation therapy (RT) and androgen suppression therapy (AST) vs RT alone. However, there are several serious problems with this study that limit its validity.

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