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December 13, 2000

Antiretroviral Therapy and Mortality Among Children With Perinatal HIV Infection—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor


Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

JAMA. 2000;284(22):2871-2872. doi:10.1001/jama.284.22.2869

In Reply: Mr Teglas and colleagues raise the important issue of selection bias in longitudinal studies to estimate the survival of HIV-infected individuals and suggest that our study's estimated cumulative probability of survival, which is lower than that reported elsewhere, may have been affected by such a bias. Although we agree that enrolling all children at birth would represent an improvement, the ideal study would enroll a very large sample of HIV-infected women and follow up those who became pregnant and, afterward, their children.

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