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December 20, 2000

Treatment of Mild Depression in Elderly Patients

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor


Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

JAMA. 2000;284(23):2993-2994. doi:10.1001/jama.284.23.2993

To the Editor: Although I applaud the effort by Dr Williams and colleagues1 to recognize and treat depression in elderly patients, I am concerned about their choice of paroxetine for this study population. Patients enrolled in this study had a mean age of 71 years. Patients with moderate or severe cognitive impairment, as defined by a Folstein Mini-Mental State Examination (MMSE) score of 23 or less, were excluded. A low MMSE score is a nonspecific finding and could indicate either dementia or delirium.

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