[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
January NaN, 2001

Dextromethorphan and Ecstasy Pills

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;285(4):409-410. doi:10.1001/jama.285.4.407

To the Editor: In their Research Letter, Mr Baggott and colleagues1 report that they performed a chemical analysis of 3,4-methylenedioxymethamphetamine (MDMA) tablets, also known as "ecstasy," and found that such tablets frequently contain dextromethorphan. The authors imply that findings of "lethargy or hyperexcitability, tachycardia, ataxia, and nystagmus, as well as a phencyclidine-like psychosis" can occur only in dextromethorphan toxicity. Furthermore, they suggest that these findings in patients admitting ecstasy use, but in whom the results of toxicology screens are negative for MDMA and amphetamines, should lead clinicians to consider dextromethorphan toxicity. Both of these statements are misleading.

First Page Preview View Large
First page PDF preview
First page PDF preview