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March 21, 2001

Hepatic γ-Cystathionase Deficiency in Patients With AIDS

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;285(11):1444-1445. doi:10.1001/jama.285.11.1444

To the Editor: Patients infected with the human immunodeficiency virus (HIV) exhibit low plasma cysteine levels at all stages of the disease.1 Glutathione (GSH) levels are also reduced in plasma, T lymphocytes, erythrocytes, and lung epithelial-lining fluid in patients with HIV infection.2,3

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