Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001
In Reply: The PPP was first developed in 1988 to assist physicians in complying with the requirements of the package insert. The program consists of a system to inform patients about the risks and benefits of isotretinoin and to evaluate a patient's ability to comply with the requirement to not be or become pregnant during the course of therapy. In addition, it provides tools for the prescriber to obtain informed consent and educational material, which would reinforce the prescriber's instructions.
Ellison RH, Leach EE. Isotretinoin and Pregnancy—Reply. JAMA. 2001;285(16):2079-2081. doi:10.1001/jama.285.16.2079