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May 9, 2001

Thiazide Use and Reduced Sodium Intake for Prevention of Osteoporosis

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;285(18):2323-2324. doi:10.1001/jama.285.18.2323

To the Editor: I was disappointed that, in the National Institutes of Health (NIH) Consensus Statement on osteoporosis,1 no mention was made of data showing that thiazide diuretics prevent the disease. At usual antihypertensive doses, thiazides have been shown to preserve bone mineralization at the wrist, elbow, and heel,2 and the hip and spine.3 More importantly, the incidence of hip fracture is reduced by 30% in those patients taking thiazides.4,5

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