Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
To the Editor: Dr Kline and colleagues1 concluded that D-dimer assay and ADSM should be used together to exclude the presence of a PE. They reported a sensitivity of 98.4% and a specificity of 51.6% for the 2 tests combined. In their study population, the prevalence of PE was 16.8%, and if both tests were normal, they estimated a 0.75% posterior probability of having a PE.
Fink KS, Miller WC. Bedside Diagnostic Tests for Pulmonary Embolism. JAMA. 2001;285(18):2326-2327. doi:10.1001/jama.285.18.2326