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June 20, 2001

Histamine Poisoning From Seafood—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;285(23):2977-2978. doi:10.1001/jama.285.23.2977

In Reply: Drs Su and Nelson comment that there is insufficient evidence that increased consumption of seafood has resulted in more cases of histamine poisoning. Our article merely suggests an explanation for a reported increase in cases during a specified time in North Carolina. It is biologically plausible, however, that more fish consumption would likely result in a higher incidence of seafood-related illness, especially in the preparation of ground tuna using belly meat scraps.

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